2 This can make you experience drowsiness much more quickly than if you were drinking alcohol alone. Pfizer, the manufacturer of Zoloft (in which sertraline is the active ingredient), also recommends avoiding alcohol while using sertraline, as the two mixed may cause you to experience an increase in drowsiness. If I were you I'd either knock it on the head or accept that it's going to make you feel crappy for a while. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It might be best to stop drinking alcohol until you see how the medicine makes you feel. Studies on alcohol and Zoloft have shown little data. Sertraline concentrate contains alcohol, and is therefore contraindicated with disulfiram (Antabuse). It’s probably a good idea to avoid all alcoholic beverages if you have depression or anxiety. We comply with the HONcode standard for trustworthy health information -, Drug class: selective serotonin reuptake inhibitors. will they interact?" Also if you experience side effects and are drinking how are you going to distinguish between hung over and side effect of the drug? So the best you can do is steer clear of alcohol for the time being. When I first started taking Sertraline I noticed some sexual side effects, these balanced out over the first few weeks and I was almost normal. Yes, alcohol reduces the inhibitions and can be a depressant to, especially if you get drunk and then sober up. If you’re invited to an event that’s likely to involve alcohol, keep taking sertraline as your doctor prescribed and consider skipping the booze and drinking a non-alcoholic beverage instead. Sertraline and alcohol combination translates to an unusual presentation of side effects such as excessive drowsiness, gross impairment of attention, judgment, and thinking. Sertraline is thought to work by increasing the amount of serotonin that’s active in your brain. Alcohol may seem to improve your mood in the short term, but its overall effect increases symptoms of depression and anxiety. Pfizer, the manufacturer of Zoloft (in which sertraline is the active ingredient), also. In this article, we’ve gathered the top 20 questions people ask about sertraline and put together a handy list of FAQs about this very common drug. Both medications work similarly in the body. Is it Safe to Drink Alcohol While Using Sertraline? However, if you use an SSRI such as sertraline (brand name: Zoloft®), you may want to think twice before you pop that next bottle. Select one or more newsletters to continue. The FDA recommends avoiding alcohol consumption while using sertraline. You should avoid or limit the use of alcohol while being treated with sertraline. Alcohol does not affect how sertraline works in the body, so you can drink alcohol while taking it. recommends avoiding alcohol while using sertraline, recommended to avoid alcohol while taking sertraline, CCPA: Do Not Sell My Personal Information. Alcohol itself can worsen the symptoms of depression. If you use sertraline to treat depression or anxiety-related conditions, you should take it exactly as  your doctor tells you to, which most likely means you shouldn’t skip a dose. For example, in patients with an earlier onset of alcoholism and high levels of both pre-morbid and alcohol-related problems [i.e., Type B alcoholics 6], fluoxetine resulted in poorer alcohol-related treatment outcomes than placebo. The prescribing information recommends that treatment of the elderly and patients with liver impairment "must be approached with caution." Effects and are drinking how are you going to distinguish between hung over and effect. 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