I drink lots of water, eat prunes and just added a fiber cereal. I know it takes a few days for the side effects to really kick in but I’m scared I’m going to be so tired from weekly infusions hat I won’t. They have antibiotic properties but also proved to be some of the most potent chemotherapies ever found; anthracyclines are used to treat 1 million cancer patients each year, particularly those with leukemia and breast cancer. Next week I will start Taxol. While in Florida, one night I woke up with extreme pain in my hip, for which I took Iboprufen and 20 minutes later it was gone. Many other chemotherapy agents cause peripheral neuropathy and ice chips or local cryotherapy have been shown to reduce neuropathic symptoms,” said Saria. I had to find that inner strength in me again to just do it, focus on 1 day at a time And oh yes, it is difficult for me to “drink water”. Taxol (paclitaxel) is a cancer chemotherapy medication that interferes with the growth of cancer cells and slows their growth and spread in the body and is used to treat breast cancer, lung cancer, and ovarian cancer.Taxol is also used to treat AIDS-related Kaposi's sarcoma.Side effects of Taxol include: increased blood pressure, fever, flushing (skin warmth or redness), Made me question my very being and if i can really do it. I’ve just concluded my fourth (and, thankfully, final) two-week cycle of Adriamycin/Cytoxin; in a week, I begin 4 biweekly Taxol treatments. I managed to keep my eyebrows and lashes until my last chemo treatment. This has only added stress and lessened sleep—for me and my husband. The 1st round was a walk in the park. This site does not provide medical advice, diagnosis, or treatment. Women who got Taxol or Taxotere once a week instead of every 3 weeks seemed to have less severe side effects from the chemotherapy. With Taxol, I felt alert and comfortable. I have to take Frmara as well as the chemo. I would ask your Doc about the 72 hour infusion, perhaps you can get a bag thing around your waist and take it home. If I got through – you can too!!!! The second half of the process was a treatment affectionately known as the “red devil” among cancer bloggers. I’m going to dance while I can… :D. I was able to do 3 of my 4 planned AC treatments but heart arrhythmia and a- fibs caused my doctors to cancel the 4th AC round and start my 12 weekly taxol treatments early. You are viewing a Navigating Care library resource. The 1st Taxol treatment went well with all the premeds given for prevention of side effects. Even an occasional e-mail or text from an acquaintance is greatly appreciated. So we start as. Sleep was my best friend. Brand name: Taxol Chemical name: Paclitaxel Class: Taxane chemotherapy.Abraxane and Taxotere are other taxanes.. How it works: Taxanes interfere with the ability of cancer cells to divide. For more information, see the 'Expert Resources' tab below. On the 4 treatment, no longer had to take medication! This is probably because each Taxol or Taxotere dose was slightly less than half the standard dose. The red devil was easier on me, made me a little sick but easily controlled with meds. 2017, CT scan without contrast, clean bill of health. I have been snowboarding twice and started a clogging class yesterday. The exercise routine has been very helpful because it gives me a sense of “normalcy”. I still have neuropathy, but its … (800) 925-4456 | Bewy 22 that result sounds spectacular! First symptom that pushes me is I have a period/heavy vaginal bleeding for 8 days after and then a lighter period for the next week every time I get the A/C. So far I’ve had 2 of the 12 and only feel tired and achy. I was in the hospital overnight, given tests, had other tests ordered, and was put on anti-seizure medication. I followed her advise and helped me a lot. The next day at the clinic I again felt light-headed and nauseous. What were the specific side effects that you experienced while taking this medication? I thank God everyday for my understanding husband who had suffered probably more than I have. I started A/C on April 17. Taxol helped save my life. Found a beanie like nanna’s is great for home – ok it doesn’t look great – but does it matter. I just want to rid myself of this invasive ductal triple negative cancer! who knew! I'm so glad it only lasted 2 days! Patient Engagement Portal v.6.0 | The group has a large grant from the Dutch Cancer Society to start a clinical trial next year of aclarubicin in relapsed leukemia patients. I'm Melissa and I'm a 11 yr. I ate fibre cereal / oats every day – topped with flaxseed 3 days prior to chemo and 5 days after. Doxorubicin, sold under the brand name Adriamycin among others, is a chemotherapy medication used to treat cancer. Chemotherapy can affect your ability to have children, whether you're a man or woman. I’ve got 4 infusions to go & lost a cohort to death of all over body cancer, & now just not the brave strong courageous positive person I was for the first 16 weeks worth. The A/C chemo combination is rough, but taxol is worse! Several doctors suggested the cause of the “seizures” may have been low blood sugar or low blood pressure. I feel like a chronic whiner, I always have pain but it moves around. You can learn about Adriamycin, a name brand chemotherapy, on WebMD.Or, if you prefer, you can check on doxorubicin, the generic term, using MedlinePlus, a comprehensive and relatively reliable public venture put forth by the National Library of Medicine and National Institutes of Health. I was given advice to get the Sancuso patch to help avoid nausea. Important Information. I was diagnosed 4 months ago when I was 41, had bilateral mastectomy with 14 lymph nodes removed between the two sides. Be able to work or function. It is expensive and may not be covered by your insurance, but mine did cover with only $20 co pay for 4 a month ( I should only need 2 if I go every 2 weeks with the A/C, don’t know if I will need for Taxol) I have been through one treatment of A/C with the patch and I had very little nausea. Sleeping through the night is not an option any more. Intravenous route (Solution) Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. and was living my old, ignorant but pain-free life. Typically, it is given after combination Adriamycin (doxorubicin), an anthracycline, and Cytoxan (cyclophosphamide) therapy. Later tests (EEG and MRI) showed that there was no evidence of seizures and the neurologist took me off that medication. Praying at night has also been helpful. Do not use Taxol without telling your doctor if you are pregnant. I did take Zantac regularly, as well as Miralax, and I occasionally took the Ondansetron for nausea. The whole time I’m taking double doses of omemprozole, pepcid ac and zantac just to try and get it under control so I can eat and drink regularly. The work, from an academic team in the Netherlands, upends conventional thinking about doxorubicin and related drugs, suggesting they do not need to directly damage DNA to kill cancer cells. YOU CAN DO IT! However, I started having TERRIBLE night sweats and occasional hot flashes about a month ago. Joy Whitlock will never forget the “red devil.” As the red chemotherapy drug pulsed through her body, it became clear to Whitlock how Adriamycin got its nickname. I’m just wondering how bad is this regimen of chemotherapy? Any one experience a splitting headache, after first ACT dense dose treatment for breast cancer? The Navigating Care Library includes articles about cancer, chemotherapy regimens and drugs from the Chemotherapy may be given by mouth, injection or infusion or on the skin, ... It’s sometimes referred to as the ‘Red Devil’ because it’s a red-colored solution,” he says. I was diagnosed with triple negative on April 3, 2018. AAAS is a partner of HINARI, AGORA, OARE, CHORUS, CLOCKSS, CrossRef and COUNTER. I have stage 4 breast inflammatory breast cancer. Xmas 2018, back ache, CT scan WITH contrast, more than 70 tumors show up, all up and down her spine. (By the way, when I have mentioned the walking to my doctor, she encourages me; medical studies are showing that gentle exercise like walking is one of the best ways of dealing with chemo side effects.) I’ve been able to walk up to 2 miles on a great day (I didn’t even consider walking an exercise before), and then I’m exhau. Yet mice prone to developing tumors that were dosed with aclarubicin did not show signs of heart damage, suggesting people treated with the drugs might be spared these effects. Trip – missy. I avoid fats, spice, acids and alcohol like the plague. It has the nickname "the red devil" due to its red color. I did 33 treatments of radiation which made me more tired than the chemo. We will get through this even when we just don’t. My name is Sarah. I just really needed to vent my TRUE feelings. I felt like an science experiment and now know I’m not alone. Hi. I’d rather do that than feel sick. Taxol is an especially versatile drug. First set of Chemo was an intense cocktail chemotherapy, Adriamycin and Cytoxan known as the “Red Devil” that was very potent but for the most part I did very well – nausea controlled by meds, tingling and numbness in hands, some upset stomach, back pain, lost of appetite and food tasting bland and red blood cell count decreasing. i had breast cancer in march 2014, had red devil and taxol chemo for 6 months, had a mastectomy and 6 weeks of radiation. Without a corporate partner, he fears, the study “may be yet another paper that is a good idea, but not really translatable.”. Can the red devil be defanged? Oddly, I never really cried then… I am so disappointed in myself and feel so bad that I want to and have screamed, wailed, and made an idiot of myself. We belong to a cycling group where nobody knows about my Cancer. I am still on femara. Best of Luck to everyone out there going through this. I’ve got a funny, fluttery feeling in my chest (like I’ve have 10 espressos!) That will be “challenging,” El-Khamisy says. Still have the odd sour cream – I want some enjoyment from food. “We’re learning more about how to make these widely used drugs less toxic.”. This is a trip that my husband and I had planned before the diagnoses. You will survive…. New forms of ‘red devil’ cancer drug could spare hearts. My Adriamycin and Cytoxan chemo regimen consisted of an infusion once every 21 days. The pain in my legs and hips was so severe I couldn’t stand up and lived on pain medication. But the researchers found doxorubicin also kills cancer cells by dislodging histones, the spherical proteins that DNA coils around like a spool to form a structure known as chromatin. I had my third round of AC yesterday. I used to exercise everyday and drink green smoothies and practice yoga. You can read of my woes of the Red Devil in my previous post. After that I will have a mastectomy or a lumpectomy plus radiation. Certification stay the course. Terms of Use | Family don’t care what you look like – they just want you there! Chemotherapy is life-saving medicine, no doubt, but it can take a severe toll on your life in the meantime. Metastaticdisease Adriamycin is sometimes combined with Cytoxan (cyclophosphamide) and/or 5-fluorouracilto make a cocktail of breast-cancer-fighting chemotherapy drugs. My mental state travels between depression and not quite normal. “We are doing what usually pharma is doing,” Neefjes says. The compounds worked as well as the original drug, if not better, at killing cultured cancer cells and were nearly as effective at slowing tumor growth in mice. By these postings it just shows how differently everyone is by way of how they react to the medication. What information would you like to pass on to patients who are beginning this medication? I would like to get out and at least do 10k steps a day but I’m so exhausted until 2 days before my next treatment. I had the same reaction as most of you. The side effects, nausea, extreme fatigue, loss of appetite and dry mouth were the worst I experienced. Researchers have tried to reduce the heart risks by, for example, packaging the drugs in fat so they will home in on tumors, with limited success. And the 4th – ankles are no where to be found – heart is pumping like a machine that is working overtime, severe headache – my first 1 in 12 weeks. Also, constipation is a problem with all the anti-nausea medicine they give. Triple Negative Breast Cancer Survivor, I’m ON taxol now. feature in order to take full advantage of this site. I don’t for drugs either – always let the body heal itself .and then it hits me . Warning. I never made to the 3 years mark though. My endocrinologist increased my diabetes medications. I can say AC was doable. I had a mastectomy on my right breast and a reduction and lift on my left. I'll be getting taxol/herceptin once a week, while I had ac every 3 weeks. Often, the most helpful information regarding treatment side effects comes not from clinical brochures, but rather from other patients like you. Last Monday I had the second treatment with AC and I have been so discouraged I too just want to quit the chemo. I always have water on hand – I don’t leave home without it. My oncologist and associated doctors (surgeon and radiation oncologist) have agreed that I’ve been fortunate with side effects to date — exhaustion, nausea (but no vomiting), minor bone pain (probably from the Neulasta shot that I get following each chemo infusion), heat flashes and extreme constipation the first week of each cycle, followed by the sense that I am gradually climbing out of a hole. The following day I rested, and read my book, on and off. I had another instance of a level of 53 and took to checking my levels every two hours throughout the night, being afraid of it going too low during the night. So I have been on A/C – 3 rounds, with 1 to go then 12 rounds of Taxol. That takes 12 days after chemo to feel decent enough, just in time for the next dose. I found sipping water frequently helped immensely with nausea and keeping things moving. The A/C has been so rough on my body and each dose has gotten harder I was about ready to throw in the towel after the 3rd dose on all of this. Barb had BC in 2001, with follow-up treatments. Now I know why I don’t do drugs. for the treatment of Breast Cancer, AC followed by Taxol is the acronym for a chemotherapy regimen used in the treatment of breast cancer, DRUGS IN THE AC FOLLOWED BY TAXOL REGIMEN. The attention and care that I am receiving from family and friends has also be of great help. Have for the most part gone off tea / coffee. The team now plans to test two potentially safer versions of doxorubicin’s drug class in people. There were times when she didn't have the energy to leave her bed. I know I react different to situations but can’t seem to stop myself. I have continued to work since first treatment back in March, only missing the day of chemotherapy. CHEMOTHERAPY I had no problems having a mastectomy and I’m not bothered by the hair loss, but the constant nausea is discouraging. Triple Negative Breast Cancer Survivor, I'm Miriam W. and I'm in treatment for Stage 2 Triple Negative Breast Cancer, I'm mariajeme, and I'm a survivor of Stage 2 Breast Cancer, I'm JennyS, and I'm a survivor of Stage 3c Breast Cancer, I'm lar, and I'm a survivor of Breast Cancer, I'm stoppeck10, and I'm a survivor of Stage 2 Breast Cancer, I'm SarahG, and I'm a survivor of Breast Cancer, I'm Randy C, and I support someone with cancer, I'm mominNC, and I'm a survivor of Breast Cancer. Doxorubicin, an old chemotherapy drug that carries this unusual moniker because of its distinctive hue and fearsome toxicity, remains a key treatment for many cancer patients. We immediately tested my blood sugar and it was very low: 53, so we took counter measures. Neither drug now has patent protection, which means companies aren’t interested, Neefjes says. Aclarubicin was once used in Europe for leukemia but was removed from the market in the 1990s because of manufacturing issues. In addition, the dexamethasone given with the treatments also raise blood sugar levels. Only two more of AC sounds doable unless you are in the midst of it. I was really dependent on my husband during the Red Devil infusions I had had. It is often used together with other chemotherapy agents. 1 doctor answer. In the context of breast cancer treatment, Adriamycin may be used for: 1. Chemotherapy is a powerful treatment that involves taking medications to damage cancerous cells. How did you manage them? 1, 2020 , 1:20 PM. (you will lose any unsaved work). 30, 2020. HER2-positivebreast cancer 3. This time I’m not so they’re giving me another week to recover. I had Chemo treatments (2½ hour sessions) every other week for 16 weeks,with three visits to the hospital for blood work, Chemo, then I go back the following day to get a shot of Neulasta to bring my white blood cell back up. Last time only 8 treatments and I kept my hair. Drug companies are the experts at the steps, like studying how a compound is metabolized and demonstrating safety, that are needed to win approval for a medicine, he notes. I’m starting to show anemia and we found out one of my prescribed meds may be contributing to the extreme fatigue I’ve been experiencing. I was already super anemic before A/C and had to get a transfusion, but I’ve had to get an iron infusion and another blood transfusion again. Of the countertop of meds that my doctor gave me to deal with side effects, she has told me that the only “must take” is Zantac; as a result, after reading the list of possible side effects from each of the side-effect meds (which in many cases seem to be even worse than the chemo side-effects they are supposed to address), I work to stop taking all except Zantac by the fourth or fifth day of each cycle. Besides breast cancer and ovarian cancer, Taxol can be used to treat several other types of cancer, including lung cancer and Kap… I had my first treatment of taxol yesterday 4/20 and right now I just feel tired but no nausea. options and managing side I’ve lost most of my muscle tone, fingernails turned yellowish-orange, I’ve lost a few toe nails that turned black and peeled off. This is about saving our life!!!. However, the upset stomach has been a constant companion. The newer "double-dose" therapy uses a combination of high dose Adriamycin and Cytoxan in combination. On the other hand, these women had to get treatment every week instead of every 3 weeks. I never wore a wig, just my bandanas and fleece hats to keep my head warm. Both drugs deserve study, he says—aclarubicin seems to work best on blood cancers whereas diMe-Doxo appears more effective for solid tumors. It had hidden in her spine for 17 years, because no one used iodide contrast in her scans. She had a double laminectomy and radiation, but she still died in my arms 30 May, 2019. Hi….my name is Sharon. I question everything about my existence and wonder if it’s worth it, if I’ll every feel good again. But, 3rd treatment, I lost most of my hair, hair is replaceable with wigs, hair pieces and hats! Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. So his team has raised money from public and private sources to produce diMe-Doxo and aclarubicin at the quality standards required for patients so they can run clinical trials as an academic effort. Doxorubicin is classified as an anthracycline, and it is used to treat breast cancer, bladder cancer, some leukemias, multiple myeloma, ovarian cancer and uterine cancer, among others (chemocare.com) 1. the National Cancer Institute and other experts. Just rocking it bald no wig because it seems the treatment has thrown me into menopause. My problems are compounded by the fact that I am diabetic and also have no working pituitary (which affects a bunch of other things), so I was already on medication for those. The 2nd set of chemo, Taxol was a little easier on me – no nausea but the tradeoff was that it made me extremely tired, my bones in my legs ached all the time and these chemo sessions were now about 6 hours long! I’m still trying to work full time so that I can get a check when I have to be out at length for surgery. Dr. ANNA KILIAN answered. I have had 3 double does and the side effects have changed from each infusion. Side effects for two days included exhaustion beyond sleepiness, nausea and depression. I have a drippy nose and my eyes are super sensitive to light for that first week as well (sunglasses in the drs office even) Yes, I lost my hair, and am exhausted. After my second treatment with AC, I was much more careful about what I ate and drank. - well up until 12 weeks ago. .it is about SAVING MY LIFE and I realize that I can handle all of it. Have moments of feeling hot – hat off – and the cold – hat on. Any wonder I have been researching just how effective these treatments are? It's also used prior to surgery in cases when it is necessary to shrink a tumor beforeit's removed (neoadjuvant chemotherapy). I ache and I’m so sore, basically from head to toe. I came here for support. 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